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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '226e55cc32f5b4faec1699c010f042f57f6cbc0dfb41b253e17edc2e569c4569' 
  AND token = '64/5709+z5wwmT8NoT0hq2hBsSGfSi6cuFjKNv1Gz+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}