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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c646f745953ab73cc9d70f9841416d1885f22e396809078357000a7536ab8ec8' 
  AND token = '+xVwoI5YU023Ic4zPdRrVP2YUrT/gR5T9jl3eNtNnV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}