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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca774c54ec73733178fa9689b0b62a3e60861c18c1a714eb57d5f7d0e946229' 
  AND token = '1p3FDdTs/5f1l0YZWhluNgzV9YdwgNWr0IuNCAEqF+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}