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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0cc4fe8625e79da9167343e4c10fc2be5b2fd4d62103f0e801b01265e462c63' 
  AND token = '6dDVCGRRcm5+aqUmS4pbIhaaa0dclgYX1tdftVNYZYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}