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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4856308fc5154f667f123e092b8ccf01662d6ecab744eaf24be028cc5ded8fee' 
  AND token = 'fizXhQXCbR60ei1ET6Zjc8/6BQ40sS/v56DQ4DMj+Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}