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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e87020de2c950767bc2a649e372a27747cb658b5c50161c5b1cb8698b2e2a1fb' 
  AND token = 'sVsx38rE7ljXs5ICm6ksFiVO0YMphfUO5hmXPtNtZeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}