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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e78c232d0c9613f412c03bdc51f72040ad99cc64a475884e8f5e6317b4b8b17' 
  AND token = 'xLZ4jeYmAXHbQm9KZQAp0F35CI18exVNQrw4I0MfuMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}