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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29b8a9a46d686d193d2c04d1708b9f8438b9eaccd5f86dc7e76b761e04b28e6f' 
  AND token = 'WNS32uKjSI/izPLsYmA63I81vt3mmCng6tSw7yiS794=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}