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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2ae4e8e5c4e732fd8c6705965de4e0d999c7d317fcde39de913e0bda7dbba40' 
  AND token = 'WMoV3SMUT4gX5EAyrkd7FBXSkN5d3EcQyWMZVlo0HGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}