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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1725f64a053582da57d3af3bbe457c78c2aeb3e001a45b7b8ad7c430adae546b' 
  AND token = 'tlSNmFdBfx2QEHNfNjGhaB39IfhoTf2gdLdRRLg8g9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}