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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f640f02daa3d7fa728d232cfe6fa6bd2ed4f096c5ef8150343b349a7101246a6' 
  AND token = 'oaFN+BSDDsN7yptgVF3FbdUrwqbChslbTsolvZqrSs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}