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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e66c972c3c742fda4611eedbf9b14f9218ce9acb6d25a0c5f4f2cbbf0713790' 
  AND token = 'g4QNvo6v1Br+Qp994yXWCcr+UQIwKk/7TEyInHsM61c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}