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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6de400355b9c38c9e9b8db9416ab7b9776c174e2d0f0cc8243d6ec56a4721b5' 
  AND token = 'PY8GxetkTFo60ApxgO8wIPWjHOS72Kv9xyBvYSUKF8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}