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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b662d7c460d36f7219bdfcfd8e83b5fc528837f23d3fd02cfaa2f900d9ad2988' 
  AND token = 'C1T2OTaC2tP3U6kfpUt4ptLHC1VePV97eN35FMkjmrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}