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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9de59dc75b49aea44be6b6f7d4af43cfb846cafdc9b72d7b427ca488087a827f' 
  AND token = 'D2CmI0EMxOGwMSSaEJl2FCJaSAqEIxqj7s/3a6FUAU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}