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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4265f08dcc2bebc8d8074666a639fe659116ededfa00861da3da125a811d9f43' 
  AND token = '245Qgje3CNni+PHWznq51lbq7tLW1OC0i8j6TpEuogo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}