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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6bb20ace1b09d59c123a7353435e926de26f76a37d01d4dd3490d2f0fa6532' 
  AND token = 'iy1EbdpS4BZ3N6bs3C8wGj7UnC+rzuHFcydGr3AT1so=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}