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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c16d10f9803e8eaa14e5f51ac7f059f4b7d491e41c4760faf8f4eafae2cf3237' 
  AND token = 'EWxrJEL6A+BRF0hVga+vZbsvIvPSWKRx/hhdW2J82Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}