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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b76a9f32107ceb426eea96a614bdf208fbe8242c09538c4fb512df2e0384bb5' 
  AND token = 'PiVMJYyDDEfBWKcJ2ztjSdBnCHUD73OkX8kNVl6wJh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}