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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa191f7491c83801d68a2a271e328adcf36a78d488e94b7e5363072ab4ebaf9c' 
  AND token = '1UwC/wTMgO4P7f19PrseWh6ZFN3s9aGupdsFMeA6mT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}