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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dfb43766600cfaa4a3eae6460974f3bc0fd53552fb13e43fd4f29034367fe2f' 
  AND token = '3dKFB09Rrjz+kAr0ADiaO9Qne6ayBNHcdVTw3CQjVqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}