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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31a262950bd5a2efc25ffe655e7ac825b308e9d2711a6f7f742113d98635bbfd' 
  AND token = 'CJ0Lmpc6Tzkp9V+1PVFugAE+yN3L9XxU8RyQBVCPHME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}