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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74eed327b95fe3cd67042216083adce99250359a451e80075a09461d152b311c' 
  AND token = 'G/3TtCVT0P9/OotFD876wT9CkQjLpBbENuKUinmG5Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}