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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05edc4fdf38706a16dcc500517a947f60b095627d9e2e1953b38e69c72970ae9' 
  AND token = '+xmOT5RD7+Ix0ElijcMznmaqDSogT/1aYU6l0K0tudc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}