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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ea4492872983e46cfcd2573e400a699bc6a786cabf8a13a68788d4c12e12a5' 
  AND token = '9txmSFL3Uh6dkF/k4CpN28CK33GVn6tLlHU8/MwwOrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}