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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8ce0de78c2487ad536d254d6320bb3346f4fbcbfda222a5ee6d3b3006ab0f77' 
  AND token = 'R0pv7+UCFDAERXpZflKxNPF3FLLwdL2eS5F8qCFCL7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}