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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6100f9b30fd1dbf64e6e9efce48e5a9a0e2cf744f19c6314cbea27f53de2be9' 
  AND token = 'snt84Av/suo+wYCgjvTppBAfFrufWIhU5U9YFhrL+Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}