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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a373bcecfd9cc8b7d28ceed38069adfd501f139535a30d9e05e6190395f7fb55' 
  AND token = 'Tspkgr3bmnA0mQVmLjvRFs4/mP+Plfq71Uj8TDtNywg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}