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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75aa788c92cd52afb99ee7571cd89af4c9a7ca9ccec7ea0c60cce0f2afc7e141' 
  AND token = 'HWqQLALZ4C5kAOFvxxk4UEBbo0sJyxqPZ7QylGi/Y30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}