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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46585ea53dbe91ebb44726d14194dbbdeca63cb974e131f648f7bd2cc256ba06' 
  AND token = 'kuRKoTwvGSu4p+UZ+L8lT4gVZIUUZe3y08plnFV1mRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}