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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03035d97f09784edafdceea4979eadb133dd3c33d4fd8a75af0dc25987a5c643' 
  AND token = 'vZ+3sSPzLwPlLVSfNdf+aGlRImyPb7TYYd5LZFa9AxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}