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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81eed7724894c04fcb8ca36b1e229e710fb3686fd2d16f4c4803016d9be7aba0' 
  AND token = '4xATrahrjZMxVjZDhG9ReSx8ISocspvh/ohhN6DJGzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}