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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e66c417ec1fe1b62ffd971240bc6f01863133b33e9d7a354cb25ae2dd2efb43a' 
  AND token = 't0hhWhb2SWeWOMnFIwxgLp/35vuy3QmjsXW+NqLM2qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}