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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdc0ed21cf2d69822a91dff6fd4b26969920a0263195036bfa7f3e6511861207' 
  AND token = 'A/ps4mQZzR7sltkLHaOVXS8XdigmFj4f3rcGBRusmIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}