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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606fa7886f34c0de723401cc889b8d4cf50b0992eeea3f64e97fadeb0e98fda2' 
  AND token = 'S0H9PBM0kH+nC9HRXZamGuHFdEXiI5ck5Qw7Rk9Bo+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}