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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42ed7ac1a137050af02019d9d2a7be171a160a4bde8d293afa98d231314cd295' 
  AND token = 'Hy5aDtrJCaMXeNBZgohEHIGDpq0AGSl/2BDQq17oyTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}