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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42cf80779ac10c3c09501a688c3cbfb6149ef261042fc83ed70b901fc9f2a4f' 
  AND token = 'X9Ywx74a6fJJ1mkWC3TdOGDqSjP9vtCMSptYFSrow7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}