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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc8c33115ab328420f1215e82f0c70c9e5f84b188b6fdbb621fb0f89f1e1f041' 
  AND token = 'fmmf6tUM5FX5829hwlbQyRrjHUUheqZsa96y21tTvO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}