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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f1a02a5e502aa902bbbd10f8e07c76537ebd348b7f4a6aa1612244ea77ddf96' 
  AND token = 'pGIoQTHSFca434Gd0VWeylOeRUgL+MnOaYrpybnju5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}