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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '683d5dfd3aa69632f1dbc9ee8721896f4c2cf41d272b14052f6253d141b42467' 
  AND token = '4N+GO4BuxrrIqs6DBLUaK9ngjkS19C2afFz0SfiSI34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}