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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78ed3b064a0da38008a8a22ebdbee793a29d6a9d872a34f9219ea2858f1e447' 
  AND token = 'Hk+xgcu/l5Zc33IhvrSc9zEo7IaMNT1ymu7LjnycLTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}