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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2a510c5716fac52428ffe922f8d16272f8eb0471c1a4c69ef94345346c18b2e' 
  AND token = 'o3PeZEQRmchK9/qQD1/ubizPEtzP04owx+goqD+QcwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}