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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fff602a5c353c5eea3d996a8ea508075f43b9ae93ee87edc886b03c9de9ef59' 
  AND token = 'oQyMZiHKuZiCOQ9P+sxZow/DEdYF9JMLsJNEG38kqMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}