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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8b98f1a0b6af8e80c3ca442ace2418b344065be863f44fecfb363f22f1702af' 
  AND token = 'IDNjw3c2HntwrQeXhTZBLkpuRkv3ODwPG93rVXvAlRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}