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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ada80d766acca27dec28fe046dffb9d5d75cca85a22ab563607ba982b89a7487' 
  AND token = 'TvpD+t7mGisA32q9DCeuyXW7LVN2mzU7G2BmRS9bwC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}