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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e35af61b566d68fd3adb14fa48abd44c65c2aafa0449f797f36e5008550d5f5' 
  AND token = '2fAWXGz0qBzl2ZLhAasXRJWcdYVfN6gNHPaWuupJlAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}