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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85e33b682539dfb07b7cc5cefd5b70761821d2ddfc1f6710198ec53210fe3040' 
  AND token = '43fDSdT2VYKmvz31mNh8lMUFWzO0c3fD8iVmY2rjM60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}