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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e02643d92ea13ccea361a427dc3016be6b8864707f626e7322a1420bdcea3886' 
  AND token = 'JS4DXebYcyywQHEZ+YmezcqeH7/FjSDo620eRbRhPLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}