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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9af0a21365e5fe4423628af6afcd2f20a575b10e7a3a594d5f9d437665b0392' 
  AND token = 'tZ/rQfRHkzkJopNvCzYi1A49MuH9GaR/dKJKSxRW4U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}