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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a06db56c08a2b15caf3452d65cc16d5aa56f30d37add7fd149c223ac14dc8b29' 
  AND token = '3A0oqQ24Uc8cO/sgK2YbwgVsJU1fWDCXC6ySlUN1KiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}